New from Phosphosolutions, a set of phospho specific Anti-NMDA Receptor (NR2B subunit) antibodies

17/12/2009
Phosphosolutions offer a set of affinity purified phosphospecific polyclonal antibodies that are all specific against the NR2B sub unit of the NMDA receptor. This subunit is mainly present in immature neurons and in extra synaptic locations.

The NMDA receptor is a specific type of ionotropic glutamate receptor. Activation of NMDA receptors results in the opening of an ion channel that is non-selective to cations. This calcium flux through NMDA receptors is thought to play a critical role in synaptic plasticity, a cellular mechanism for learning and memory.

The NMDA receptor has been associated with several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. It also has been proven to be one of the principal molecular targets for alcohol in the central nervous system.

These antibodies are usable for western blot and immunohistochemistry with samples of wide variety of species.

Phosphosolutions

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